Cancer and Leukaemia

Cancer and Leukaemia

Author: Jan de Vries

Publisher: Random House

ISBN: 9781780571058

Category: Health & Fitness

Page: 160

View: 135

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What are the causes of cancer, and is there a cure for this most devastating of diseases? Why is it that some parts of the world show a dramatic rise in the cancer rate of those under 25? Why is bowel cancer incidence substantially higher in Scotland than in the rest of Britain? And why is the UK incidence of cancer the second highest in the world? These and other vital questions are discussed in Cancer and Leukaemia: An Alternative Approach.

Childhood Leukemia and Cancer, An Issue of Pediatric Clinics, E-Book

Childhood Leukemia and Cancer, An Issue of Pediatric Clinics, E-Book

Author: Yaddanapudi Ravindranath

Publisher: Elsevier Health Sciences

ISBN: 9780323354660

Category: Medical

Page: 353

View: 215

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This issue concentrates on the current evidence and the collected experience of pediatric oncologists who care for cancer patients. The individual articles will provide the general pediatrician with a comprehensive primer on diagnosing and managing various types of cancers in the child with cancer. A cancer diagnosis is no longer a death sentence, so management and monitoring is very important and covered in every article.

Experimental Leukemia and Mammary Cancer

Experimental Leukemia and Mammary Cancer

Author: Charles Huggins

Publisher: University of Chicago Press

ISBN: 0226358607

Category: Medical

Page: 252

View: 161

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Charles Brenton Huggins won the Nobel prize in 1966 for his extensive work in cancer research. He has spent fifty years at the laboratory bench exploring the nature of this disease in an attempt to understand and control it. In this volume, based almost exclusively on experiments conducted over the past twenty years at the University of Chicago, is both the record of Huggins's own research and, in Huggins's words, "a do-it-yourself guide for cancer research workers." Written simply and clearly so that the experiments can be easily reproduced, the book presents Huggins's experiments in the induction of breast cancer and leukemia in rodents. It also describes the methods he discovered to prevent cancer and to cure many of the cancers he has been able to induce. Although most of the material concerns breast cancer and leukemia, research on other kinds of tumors is also described.

Cancer and its Management

Cancer and its Management

Author: Jeffrey S. Tobias

Publisher: John Wiley & Sons

ISBN: 9781118468739

Category: Medical

Page: 626

View: 544

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Now in its seventh edition, this highly-regarded book is designed as an introductory and reference text on the principles of diagnosis, staging, and treatment of tumors. As for the last 6 editions of the book, the aim and scope of the new edition are once again to provide a thorough yet reasonably brief account of the whole field of oncology, focusing on the latest principles of cancer management. The book is already well established, having been first published in 1986 and in continuous print since then. The authors are rightfully proud of their strong legacy of providing carefully revised new editions of this standard and well-received cancer text for audiences in the UK and abroad. Oncology is a very rapidly changing speciality, with many new treatments and even treatment modalities coming on stream with bewildering speed. Besides a thorough general updating of the text, figures, and tables, the new seventh edition adds a new chapter on Molecular Targeted Therapy, making the book 30 chapters in total. This accessible and practical resource is invaluable to trainees and specialists alike in oncology, palliative care and general medicine, as well as specialist nurses, general practitioners, medical students, and professions allied to medicine.

RUNX Proteins in Development and Cancer

RUNX Proteins in Development and Cancer

Author: Yoram Groner

Publisher: Springer

ISBN: 9789811032332

Category: Medical

Page: 515

View: 963

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This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29 chapters, humans and other mammals have three RUNX genes that are known to play specific roles in blood, bone and neuronal development. However, their evolutionary history has recently been traced back to unicellular organisms and their involvement in many well-known signaling pathways (Wnt, TGFb, Notch, Hippo) is indicative of a more general function in cell biology. Their documented roles in cell fate decisions include control of proliferation, differentiation, survival, senescence and autophagy. The pleiotropic effects of RUNX in development are mirrored in cancer, where RUNX genes can function as oncogenes that collaborate strongly with Myc family oncogenes or as tumour suppressor genes. In the latter role, they display hallmarks of both ‘gatekeepers’ that modulate p53 responses and ‘caretakers’ that protect the genome from DNA damage. Several chapters focus on the importance of these genes in leukemia research, where RUNX1 and CBFB are frequently affected by chromosomal translocations that generate fusion oncoproteins, while recent studies suggest wider roles for RUNX modulation in solid cancers. Moreover, RUNX genes are intimately involved in the development and regulation of the immune system, while emerging evidence suggests a role in innate immunity to infectious agents, including HIV. At the biochemical level, the RUNX family can serve as activators or repressors of transcription and as stable mediators of epigenetic memory through mitosis. Not surprisingly, RUNX activity is controlled at multiple levels, this includes miRNAs and a plethora of post-translational modifications. Several chapters highlight the interplay between the three mammalian RUNX genes, where cross-talk and partial functional redundancies are evident. Finally, structural analysis of the RUNX/CBFB interaction has led to the development of small molecule inhibitors that provide exciting new tools to decipher the roles of RUNX in development and as targets for therapy. This volume provides a compendium and reference source that will be of broad interest to cancer researchers, developmental biologists and immunologists.

Cancer Chemotherapy: an Introduction

Cancer Chemotherapy: an Introduction

Author: Terry J. Priestman

Publisher: Springer Science & Business Media

ISBN: 9781447116868

Category: Medical

Page: 209

View: 778

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This book is intended as an introduction to the drug treatment of cancer. It is almost ten years since the last edition was written. In the intervening time, there have been numerous developments in cancer chemotherapy and in order to cover these the majority of the text has been completely revised and rewritten. In addition, two new chapters have been introduced, one on the safe handling of cytotoxic drugs and the other on biological response modifiers. In order to incorporate this new information without any undue increase in the length of the text the chapters on a combined approach to treatment have been omitted. This is not because interdisciplinary collaboration is no longer considered important but is a reflection of the fact that, in most centres, it has become the norm in cancer management and its central role in successful treatment no longer needs to be stressed quite so strongly. The four chapters in the last edition which dealt with the team approach to cancer therapy have been replaced by a single chapter on the place of chemotherapy in the overall treatment of cancer. Unfortunately, despite all the innovations of the last decade, it has become increasingly clear that much of the promise offered by drug treatment during the 1960s and 1970s has not been fulfilled.

Nutrition during Blood cancer (leukemia)

Nutrition during Blood cancer (leukemia)

Author: Josef Miligui

Publisher: BoD – Books on Demand

ISBN: 9783746025865

Category: Cooking

Page: 61

View: 271

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di-book - nutritional counseling after syndromes - Diet recommendations, recipes and food supplements for supporting the therapy. The recipes help you to cook tasty dishes. All recipes with cooking instructions, calorie indications and description of the effect. The foods are shown in categories recommended, yes, little and no and help you to orientate if your own recipes should be cooked.

Childhood Leukemias

Childhood Leukemias

Author: Ching-Hon Pui

Publisher: Cambridge University Press

ISBN: 0521581761

Category: Medical

Page: 604

View: 99

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Childhood Leukemias, edited by Dr Ching-Hon Pui, is the most clinically-oriented and authoritative reference dedicated to these diseases.