Applied Survival Analysis

Applied Survival Analysis

Author: David W. Hosmer, Jr.

Publisher: John Wiley & Sons

ISBN: 9781118211588

Category: Mathematics

Page: 416

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THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.

Applied Survival Analysis Using R

Applied Survival Analysis Using R

Author: Dirk F. Moore

Publisher: Springer

ISBN: 9783319312453

Category: Medical

Page: 226

View: 504

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Applied Survival Analysis Using R covers the main principles of survival analysis, gives examples of how it is applied, and teaches how to put those principles to use to analyze data using R as a vehicle. Survival data, where the primary outcome is time to a specific event, arise in many areas of biomedical research, including clinical trials, epidemiological studies, and studies of animals. Many survival methods are extensions of techniques used in linear regression and categorical data, while other aspects of this field are unique to survival data. This text employs numerous actual examples to illustrate survival curve estimation, comparison of survivals of different groups, proper accounting for censoring and truncation, model variable selection, and residual analysis. Because explaining survival analysis requires more advanced mathematics than many other statistical topics, this book is organized with basic concepts and most frequently used procedures covered in earlier chapters, with more advanced topics near the end and in the appendices. A background in basic linear regression and categorical data analysis, as well as a basic knowledge of calculus and the R system, will help the reader to fully appreciate the information presented. Examples are simple and straightforward while still illustrating key points, shedding light on the application of survival analysis in a way that is useful for graduate students, researchers, and practitioners in biostatistics.

Applied Survival Analysis

Applied Survival Analysis

Author: Chap T. Le

Publisher: Wiley-Interscience

ISBN: 0471170852

Category: Mathematics

Page: 280

View: 176

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This concise, application-oriented text is designed to meet the needs of practitioners and students in applied fields in its coverage of major, updated methods in the analysis of survival data. Includes analysis of standardized mortality ratios, methods for proving attenuation of healthy worker effects, ordinal risk factors and other new areas of research. Timely and diverse case studies are presented, plus a complete data set on ESRD patients on hemodialysis. Moderate level of mathematics required.

Applied Survival Analysis

Applied Survival Analysis

Author: David W. Hosmer, Jr.

Publisher: Wiley-Interscience

ISBN: STANFORD:36105025984183

Category: Mathematics

Page: 414

View: 988

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A Practical, Up-To-Date Guide To Modern Methods In The Analysis Of Time To Event Data. The rapid proliferation of powerful and affordable statistical software packages over the past decade has inspired the development of an array of valuable new methods for analyzing survival time data. Yet there continues to be a paucity of statistical modeling guides geared to the concerns of health-related researchers who study time to event data. This book helps bridge this important gap in the literature. Applied Survival Analysis is a comprehensive introduction to regression modeling for time to event data used in epidemiological, biostatistical, and other health-related research. Unlike other texts on the subject, it focuses almost exclusively on practical applications rather than mathematical theory and offers clear, accessible presentations of modern modeling techniques supplemented with real-world examples and case studies. While the authors emphasize the proportional hazards model, descriptive methods and parametric models are also considered in some detail. Key topics covered in depth include: * Variable selection. * Identification of the scale of continuous covariates. * The role of interactions in the model. * Interpretation of a fitted model. * Assessment of fit and model assumptions. * Regression diagnostics. * Recurrent event models, frailty models, and additive models. * Commercially available statistical software and getting the most out of it. Applied Survival Analysis is an ideal introduction for graduate students in biostatistics and epidemiology, as well as researchers in health-related fields.

Analysis of Survival Data

Analysis of Survival Data

Author: D.R. Cox

Publisher: Routledge

ISBN: 9781351466608

Category: Mathematics

Page: 116

View: 566

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This monograph contains many ideas on the analysis of survival data to present a comprehensive account of the field. The value of survival analysis is not confined to medical statistics, where the benefit of the analysis of data on such factors as life expectancy and duration of periods of freedom from symptoms of a disease as related to a treatment applied individual histories and so on, is obvious. The techniques also find important applications in industrial life testing and a range of subjects from physics to econometrics. In the eleven chapters of the book the methods and applications of are discussed and illustrated by examples.

Studyguide for Applied Survival Analysis

Studyguide for Applied Survival Analysis

Author: Cram101 Textbook Reviews

Publisher: Academic Internet Pub Incorporated

ISBN: 1617440205

Category: Education

Page: 152

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Never HIGHLIGHT a Book Again! Virtually all of the testable terms, concepts, persons, places, and events from the textbook are included. Cram101 Just the FACTS101 studyguides give all of the outlines, highlights, notes, and quizzes for your textbook with optional online comprehensive practice tests. Only Cram101 is Textbook Specific. Accompanys: 9780471754992 .

Dynamic Prediction in Clinical Survival Analysis

Dynamic Prediction in Clinical Survival Analysis

Author: Hans van Houwelingen

Publisher: CRC Press

ISBN: 9781439835432

Category: Mathematics

Page: 250

View: 688

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There is a huge amount of literature on statistical models for the prediction of survival after diagnosis of a wide range of diseases like cancer, cardiovascular disease, and chronic kidney disease. Current practice is to use prediction models based on the Cox proportional hazards model and to present those as static models for remaining lifetime after diagnosis or treatment. In contrast, Dynamic Prediction in Clinical Survival Analysis focuses on dynamic models for the remaining lifetime at later points in time, for instance using landmark models. Designed to be useful to applied statisticians and clinical epidemiologists, each chapter in the book has a practical focus on the issues of working with real life data. Chapters conclude with additional material either on the interpretation of the models, alternative models, or theoretical background. The book consists of four parts: Part I deals with prognostic models for survival data using (clinical) information available at baseline, based on the Cox model Part II is about prognostic models for survival data using (clinical) information available at baseline, when the proportional hazards assumption of the Cox model is violated Part III is dedicated to the use of time-dependent information in dynamic prediction Part IV explores dynamic prediction models for survival data using genomic data Dynamic Prediction in Clinical Survival Analysis summarizes cutting-edge research on the dynamic use of predictive models with traditional and new approaches. Aimed at applied statisticians who actively analyze clinical data in collaboration with clinicians, the analyses of the different data sets throughout the book demonstrate how predictive models can be obtained from proper data sets.

Survival Analysis with Long-Term Survivors

Survival Analysis with Long-Term Survivors

Author: Ross A. Maller

Publisher: John Wiley & Sons

ISBN: UVA:X004104251

Category: Mathematics

Page: 312

View: 830

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The aim of this book is to suggest and exemplify a systematic methodology for analysing survival data which contains "immune", or "cured" individuals, denoted generically as "long-term survivors". Such data occurs in medical and epidemiological applications, where the intention may be to identify whether or not cured or immune individuals are present in a population, perhaps as a result of treatments given; in the analysis of recidivism data in criminology, where the intentions are similar with respect to prisoners released from and possibly returning to prison; and in many other areas where followup data is available on individuals, with the possibility that not all suffer the event under investigation. Both nonparametric and parametric methods are proposed and developed. The effects of covariate information can be assessed via a kind of generalised linear framework in the parametric analyses. The proposed methodologies are supported by asymptotic analyses and simulations of real situations. While these theoretical underpinnings are presented in reasonable rigour and detail, the book is aimed very much at the practitioner who wishes to analyse survival data with (or even without) immunes.

Reliability and Survival Analysis

Reliability and Survival Analysis

Author: Md. Rezaul Karim

Publisher: Springer

ISBN: 9789811397769

Category: Medical

Page: 252

View: 999

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This book presents and standardizes statistical models and methods that can be directly applied to both reliability and survival analysis. These two types of analysis are widely used in many fields, including engineering, management, medicine, actuarial science, the environmental sciences, and the life sciences. Though there are a number of books on reliability analysis and a handful on survival analysis, there are virtually no books on both topics and their overlapping concepts. Offering an essential textbook, this book will benefit students, researchers, and practitioners in reliability and survival analysis, reliability engineering, biostatistics, and the biomedical sciences.

Analysis of Failure and Survival Data

Analysis of Failure and Survival Data

Author: Peter J. Smith

Publisher: CRC Press

ISBN: 1584880759

Category: Mathematics

Page: 268

View: 499

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Analysis of Failure and Survival Data is an essential textbook for graduate-level students of survival analysis and reliability and a valuable reference for practitioners. It focuses on the many techniques that appear in popular software packages, including plotting product-limit survival curves, hazard plots, and probability plots in the context of censored data. The author integrates S-Plus and Minitab output throughout the text, along with a variety of real data sets so readers can see how the theory and methods are applied. He also incorporates exercises in each chapter that provide valuable problem-solving experience. In addition to all of this, the book also brings to light the most recent linear regression techniques. Most importantly, it includes a definitive account of the Buckley-James method for censored linear regression, found to be the best performing method when a Cox proportional hazards method is not appropriate. Applying the theories of survival analysis and reliability requires more background and experience than students typically receive at the undergraduate level. Mastering the contents of this book will help prepare students to begin performing research in survival analysis and reliability and provide seasoned practitioners with a deeper understanding of the field.

Survival Analysis

Survival Analysis

Author: John P. Klein

Publisher: Springer Science & Business Media

ISBN: 9780387216454

Category: Medical

Page: 538

View: 692

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Applied statisticians in many fields must frequently analyze time to event data. While the statistical tools presented in this book are applicable to data from medicine, biology, public health, epidemiology, engineering, economics, and demography, the focus here is on applications of the techniques to biology and medicine. The analysis of survival experiments is complicated by issues of censoring, where an individual's life length is known to occur only in a certain period of time, and by truncation, where individuals enter the study only if they survive a sufficient length of time or individuals are included in the study only if the event has occurred by a given date. The use of counting process methodology has allowed for substantial advances in the statistical theory to account for censoring and truncation in survival experiments. This book makes these complex methods more accessible to applied researchers without an advanced mathematical background. The authors present the essence of these techniques, as well as classical techniques not based on counting processes, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of Practical Notes at the end of each section. Technical details of the derivation of the techniques are sketched in a series of Technical Notes. This book will be useful for investigators who need to analyze censored or truncated life time data, and as a textbook for a graduate course in survival analysis. The prerequisite is a standard course in statistical methodology.

Applied Categorical Data Analysis

Applied Categorical Data Analysis

Author: Chap T. Le

Publisher: Wiley-Interscience

ISBN: UOM:39015055578499

Category: Mathematics

Page: 287

View: 567

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The nonstatistician's quick reference to applied categorical data analysis With a succinct, unified approach to applied categorical data analysis and an emphasis on applications, this book is immensely useful to researchers and students in the biomedical disciplines and to anyone concerned with statistical analysis. This self-contained volume provides up-to-date coverage of all major methodologies in this area of applied statistics and acquaints the reader with statistical thinking as expressed through a variety of modern-day topics and techniques. Applied Categorical Data Analysis introduces a number of new research areas, including the Mantel-Haenszel method, Kappa statistics, ordinal risks, odds ratio estimates, goodness-of-fit, and various regression models for categorical data. Chap T. Le, author of Health and Numbers and Applied Survival Analysis, presents his information in a user-friendly format and an accessible style while purposefully keeping the mathematics to a level appropriate for students in applied fields. Well supplemented with helpful graphs and tables, Applied Categorical Data Analysis: * Covers both basic and advanced topics * Employs many real-life examples from biomedicine, epidemiology, and public health * Presents case studies in meticulous detail * Provides end-of-chapter exercise sets and solutions * Incorporates samples of computer programs (most notably in SAS). Applied Categorical Data Analysis is an important resource for graduate students and professionals who need a compact reference and guide to both the fundamentals and applications of the major methods in the field.